Search results for "Benzoyl chloride"

showing 6 items of 6 documents

A Versatile and Convenient Method for the Functionalization of Porphyrins

2001

International audience; The condensation of 3-(chloromethyl)benzoyl chloride with different atropisomers of meso-(tetra-o-aminophenyl)porphyrin (TAPP), followed by the reaction of a series of nucleophilic reagents leads, among others, to precursors of biomimetic models of heme proteins such as cytochrome c oxidase (CcO). This synthesis can also be applied as an efficient two-step reaction to obtain highly functionalized porphyrin derivatives potentially useful for cation binding.

Cation bindingAtropisomerHemeproteinPorphyrinsChemistryEnzyme modelsOrganic ChemistryPorphyrinCombinatorial chemistry[ CHIM ] Chemical SciencesHeme proteinschemistry.chemical_compoundBenzoyl chlorideNucleophileReagentCationspolycyclic compounds[CHIM]Chemical SciencesOrganic chemistrySurface modificationPhysical and Theoretical ChemistryOxidoreductases
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Simple high-performance liquid chromatographic assay for polyamines and their monoacetyl derivatives.

1993

A rapid reversed-phase high-performance liquid chromatographic method, using pre-column derivatization with benzoyl chloride and ultraviolet detection at 254 nm, was developed for the simultaneous measurement of polyamines and their monoacetyl derivatives. Calibration curves were linear for concentrations from 1.25 to 25 nmol/ml. The method was employed to assay these compounds in chick embryo retina explants using organic solvent extraction and 1,7-diaminoheptane as an internal standard. This simple and sensitive method can be applied to routine determinations of these compounds in various biological samples.

ChromatographyCalibration curveOrganic solventExtraction (chemistry)Reproducibility of ResultsAcetylationGeneral ChemistryChick EmbryoDiaminesHigh-performance liquid chromatographyRetinachemistry.chemical_compoundBenzoyl chloridechemistryPolyaminesAnimalsSpectrophotometry UltravioletDerivatizationQuantitative analysis (chemistry)Chromatography High Pressure LiquidJournal of chromatography
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Rapid and simultaneous high-performance liquid chromatography assay of polyamines and monoacetylpolyamines in biological specimens

2000

A rapid, resolutive and reproducible reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed for polyamines and acetylpolyamines by adopting pre-column derivatization with benzoyl chloride. In a single run lasting less than 15 min ten polyamines were separated as well as traces of benzoic acid, methylbenzoate and benzoic anhydride. These contaminants, produced during the derivatization reaction, were almost all eliminated by washing steps envisaged in the same procedure. This simple and sensitive method can be applied to routine determination of polyamines in biological samples. A fine application of this procedure to the determination of endogenous content of p…

Chromatographymedicine.diagnostic_testorganic chemicalsBiogenic PolyaminesReproducibility of ResultsGeneral ChemistryReversed-phase chromatographyReference StandardsSensitivity and SpecificityHigh-performance liquid chromatographyBenzoic anhydridechemistry.chemical_compoundBenzoyl chloridechemistrySpectrophotometrymedicineSpectrophotometry UltravioletDerivatizationQuantitative analysis (chemistry)Chromatography High Pressure LiquidBenzoic acidJournal of Chromatography B: Biomedical Sciences and Applications
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Determination of alternative preservatives in cosmetic products by chromophoric derivatization followed by vortex-assisted liquid-liquid semimicroext…

2016

An analytical method for the simultaneous determination of phenethyl alcohol, methylpropanediol, phenylpropanol, caprylyl glycol, and ethylhexylglycerin, which are used as alternative preservatives in cosmetic products, has been developed. The method is based on liquid chromatography with UV spectrophotometric detection after chromophoric derivatization with benzoyl chloride and vortex-assisted liquid-liquid semimicroextraction. Different chromatographic parameters, derivatization conditions, and sample preparation variables were studied. Under optimized conditions, the limits of detection values for the analytes ranged from 0.02 to 0.06µgmL(-1). The method was validated with good recovery …

Detection limitAnalytePreservativeChromatographymedia_common.quotation_subject010401 analytical chemistryPreservatives Pharmaceutical02 engineering and technologyCosmeticsPhenylethyl Alcohol021001 nanoscience & nanotechnology01 natural sciencesCosmetics0104 chemical sciencesAnalytical Chemistrychemistry.chemical_compoundBenzoyl chloridechemistryPhenethyl alcoholSample preparation0210 nano-technologyDerivatizationmedia_commonChromatography LiquidTalanta
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CCDC 248093: Experimental Crystal Structure Determination

2005

Related Article: R.Abbel, H.Frey, D.Schollmeyer, A.F.M.Kilbinger|2005|Chem.-Eur.J.|11|2170|doi:10.1002/chem.200401085

Space GroupCrystallographyCrystal SystemCrystal Structure4-((chloro(4-((chloro(4-((chloro(4-nitrophenyl)methylene)amino)-phenyl)methylene)amino)phenyl)methylene)amino)benzoyl chlorideCell ParametersExperimental 3D Coordinates
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CCDC 248092: Experimental Crystal Structure Determination

2005

Related Article: R.Abbel, H.Frey, D.Schollmeyer, A.F.M.Kilbinger|2005|Chem.-Eur.J.|11|2170|doi:10.1002/chem.200401085

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates4-((chloro(4-((chloro(4-nitrophenyl)methylene)amino)-phenyl)methylene)amino)benzoyl chloride
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